To me it sounds like access rights.
In Windows 10 etc. you can't store INI files in program catalogue anymore. If you do they will automatically be moved to a virtualstore by Windows.
The answer to your question is multi faceted depending on which version of DataEase 8.5 you are using. (8.5 was the longest running version number in DataEase history).
In the latest version DATAEASE.INI which store these settings will be in
Just copy the above into the addressfield on your explorer and you will automatically get there.
In DataEase.ini there will be a section called [STARTUP]
HelpLink = http://www.dataease.com/dg3_SearchHelp/
and a section called [RECENT]
AppName1=GT Service 2013
I supect that this catalog is now write protected so you won't be able to store your changes.
You can try to edit it manually and see if you can store the changes then.
You can just give everyone all read/write/change rights on it .